Research Scientist – Developmental Immunology
Company:
Recombinetics is seeking a highly motivated and creative Research Scientist to take a leading role in cutting edge research and development project in the field of organ regeneration and interspecies chimerism. Recombinetics mission is to create identical replicas of a patient’s own organ cells and tissues — with his or her own DNA — this technology has the potential to transform the face of modern medicine and drastically improve the quality-of-life for millions.
Potential Benefits
A dynamic and highly collaborative working environment
Comprehensive benefits package available, including health, dental, vision, and 401K
Job title and compensation will be based on candidate experience
Recombinetics is an equal opportunity provider and employer
Responsibilities:
The candidate will be responsible to establish human immunology platforms for various cell culture. Perform all aspects of creating, growing and expanding cells for regenerative medicine programs.
The candidate will possess an extensive understanding of developmental immunology, hematopoietic stem cells differentiation to multiple populations of the hematopoietic lineage.
The ideal candidate will have demonstrated expertise in hematopoietic techniques, attention to detail, and quality focused mindset.
The Scientist will have full responsibility to ensure that procedures are established and followed for all cell culture processes – ensuring the highest standards in laboratory methods to provide quality results.
You will be a team member as part of a fast-paced, collaborative science team, with the expectation is to maintain close communication with other scientists.
Essential Duties and Job Functions:
The candidate must think critically and creatively and work independently. We highly value candidates with a collaborative and collegial work ethic, with the ability to deliver results in a dynamic and fast-paced team environment. The candidate should exhibit excellent organizational skills and be proficient in both data management and the preparation of summary reports. The candidate should be able to present clear and concise data summaries in group and team meetings. A milestone-driven scientist who is able to meet project timelines, completion and budget. The candidate should be willing to work weekends in rotation with other colleagues.
Knowledge, Experience and Skills:
PhD, MD in molecular immunology, developmental immunology or related science
A minimum of 4 years of hematopoietic cell culture experience, preferably human and primary culture
Expertise in culturing and differentiating mammalian pluripotent stem cells to various populations of the hematopoietic lineage
Introduce new methods, platforms and project concepts
Experience in various molecular biology methods, including: PCR, qPCR, Southern, Western, Northern, IHC, ICC, FISH, DNA cloning
Knowledge and proven experience in NGS methods: ChIP, ATAC, RNA-seq, Single-cell RNA-seq, etc.
Extensive experience with flow cytometry, specifically in characterizing multiple populations and subpopulations during embryo development
Experience with various microscopy techniques
Willingness to work with lentiviral vector and human biological samples
Maintain accurate and reliable record keeping including database management, notebooks, and all other pertinent documentation.
Ability to keep current with relevant scientific literature
Demonstrated proficiency in computer skills
Excellent problem-solving skills
Strong teamwork and collaboration skills
Ability to take ownership of projects and results
Must be able to communicate effectively in oral and written formats
Be known by their fellow colleagues as friendly and reliable
Possesses the drive to succeed and to participate in the growth of an exciting, fast-paced company
Knowledge of automated laboratory systems is a plus
Experience in genome engineering technologies such as CRISPR/Cas9 is a plus
Send CV credentials and a letter of interest to Tad Sonstegard at tad@recombinetics.com